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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q8WUP2
USC-OGP 2-DE database
:
Q8WUP2
Q8WUP2
General information about the entry
View entry in simple text format
Entry name
FBLI1_HUMAN
Primary accession number
Q8WUP2
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Filamin-binding LIM protein 1; Short=FBLP-1; AltName: Full=Migfilin; AltName: Full=Mitogen-inducible 2-interacting protein; Short=MIG2-interacting protein;.
Gene name
Name=FBLIM1
Synonyms=FBLP1
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1166
:
pI=5.55; Mw=48056
Cross-references
UniProtKB/Swiss-Prot
Q8WUP2; FBLI1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
FBLI1_HUMAN
Primary accession number
Q8WUP2
Secondary accession number(s)
B3KNY0 Q5VVE0 Q5VVE1 Q8IX23 Q96T00 Q9UFD6
Sequence was last modified on
February 6, 2007 (version 2)
Annotations were last modified on
March 15, 2017 (version 153)
Name and origin of the protein
Description
RecName: Full=Filamin-binding LIM protein 1; Short=FBLP-1; AltName: Full=Migfilin; AltName: Full=Mitogen-inducible 2-interacting protein; Short=MIG2-interacting protein;
Gene name
Name=FBLIM1
Synonyms=FBLP1
Encoded on
Name=FBLIM1; Synonyms=FBLP1
Keywords
3D-structure
;
Alternative splicing
;
Cell adhesion
;
Cell junction
;
Cell shape
;
Complete proteome
;
Cytoplasm
;
Cytoskeleton
;
LIM domain
;
Metal-binding
;
Polymorphism
;
Reference proteome
;
Repeat
;
Zinc
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AY180161; AAO49012.1
; -; mRNA
EMBL
AF459643; AAO15549.1
; -; mRNA
EMBL
AK027444; BAB55115.1
; -; mRNA
EMBL
AK055259; BAG51492.1
; -; mRNA
EMBL
AL450998; CAH70854.1
; -; Genomic_DNA
EMBL
AL450998; CAH70853.1
; -; Genomic_DNA
EMBL
BC019895; AAH19895.1
; -; mRNA
EMBL
AL133035; CAB61365.1
; -; mRNA
CCDS
CCDS163.1; -. [Q8WUP2-1]
; .
CCDS
CCDS30609.1; -. [Q8WUP2-3]
; .
CCDS
CCDS44064.1; -. [Q8WUP2-2]
; .
PIR
T42678; T42678
; .
RefSeq
NP_001019386.1; NM_001024215.1. [Q8WUP2-2]
; .
RefSeq
NP_001019387.1; NM_001024216.1. [Q8WUP2-3]
; .
RefSeq
NP_060026.2; NM_017556.2. [Q8WUP2-1]
; .
RefSeq
XP_005245957.1; XM_005245900.1. [Q8WUP2-2]
; .
RefSeq
XP_005245958.1; XM_005245901.1. [Q8WUP2-2]
; .
RefSeq
XP_005245959.1; XM_005245902.1. [Q8WUP2-2]
; .
RefSeq
XP_005245960.1; XM_005245903.1. [Q8WUP2-2]
; .
RefSeq
XP_005245966.1; XM_005245909.3. [Q8WUP2-1]
; .
RefSeq
XP_006710767.1; XM_006710704.3. [Q8WUP2-2]
; .
RefSeq
XP_006710768.1; XM_006710705.1. [Q8WUP2-2]
; .
RefSeq
XP_011539918.1; XM_011541616.2. [Q8WUP2-2]
; .
RefSeq
XP_011539919.1; XM_011541617.2. [Q8WUP2-1]
; .
RefSeq
XP_016857008.1; XM_017001519.1. [Q8WUP2-2]
; .
RefSeq
XP_016857009.1; XM_017001520.1. [Q8WUP2-2]
; .
RefSeq
XP_016857010.1; XM_017001521.1. [Q8WUP2-2]
; .
RefSeq
XP_016857011.1; XM_017001522.1. [Q8WUP2-2]
; .
RefSeq
XP_016857012.1; XM_017001523.1. [Q8WUP2-2]
; .
RefSeq
XP_016857013.1; XM_017001524.1. [Q8WUP2-2]
; .
RefSeq
XP_016857014.1; XM_017001525.1. [Q8WUP2-1]
; .
UniGene
Hs.530101; -
; .
PDB
2K9U; NMR
; -; B=1-24
PDB
2W0P; X-ray
; 1.90 A; C=5-19
PDB
4P3W; X-ray
; 2.00 A; G/H/I/J/K/L=5-28
PDBsum
2K9U; -
; .
PDBsum
2W0P; -
; .
PDBsum
4P3W; -
; .
ProteinModelPortal
Q8WUP2; -
; .
SMR
Q8WUP2; -
; .
BioGrid
120128; 10
; .
IntAct
Q8WUP2; 10
; .
STRING
9606.ENSP00000416387; -
; .
iPTMnet
Q8WUP2; -
; .
PhosphoSitePlus
Q8WUP2; -
; .
SwissPalm
Q8WUP2; -
; .
BioMuta
FBLIM1; -
; .
DMDM
125987829; -
; .
EPD
Q8WUP2; -
; .
MaxQB
Q8WUP2; -
; .
PaxDb
Q8WUP2; -
; .
PeptideAtlas
Q8WUP2; -
; .
PRIDE
Q8WUP2; -
; .
DNASU
54751; -
; .
Ensembl
ENST00000332305; ENSP00000364920
; ENSG00000162458. [Q8WUP2-3]; .
Ensembl
ENST00000375766; ENSP00000364921
; ENSG00000162458. [Q8WUP2-1]; .
Ensembl
ENST00000375771; ENSP00000364926
; ENSG00000162458. [Q8WUP2-1]; .
Ensembl
ENST00000441801; ENSP00000416387
; ENSG00000162458. [Q8WUP2-2]; .
GeneID
54751; -
; .
KEGG
hsa:54751; -
; .
UCSC
uc001axd.2; human. [Q8WUP2-1]
; .
CTD
54751; -
; .
DisGeNET
54751; -
; .
GeneCards
FBLIM1; -
; .
HGNC
HGNC:24686; FBLIM1
; .
HPA
HPA025287; -
; .
HPA
HPA072750; -
; .
MIM
607747; gene
; .
neXtProt
NX_Q8WUP2; -
; .
OpenTargets
ENSG00000162458; -
; .
PharmGKB
PA142671776; -
; .
eggNOG
KOG1701; Eukaryota
; .
eggNOG
ENOG410Y3GP; LUCA
; .
GeneTree
ENSGT00760000119039; -
; .
HOGENOM
HOG000007533; -
; .
HOVERGEN
HBG051561; -
; .
InParanoid
Q8WUP2; -
; .
OMA
NRLFCKP; -
; .
OrthoDB
EOG091G0CJO; -
; .
PhylomeDB
Q8WUP2; -
; .
TreeFam
TF320310; -
; .
Reactome
R-HSA-446353; Cell-extracellular matrix interactions
; .
ChiTaRS
FBLIM1; human
; .
EvolutionaryTrace
Q8WUP2; -
; .
GeneWiki
FBLIM1; -
; .
GenomeRNAi
54751; -
; .
PRO
PR:Q8WUP2; -
; .
Proteomes
UP000005640; Chromosome 1
; .
Bgee
ENSG00000162458; -
; .
CleanEx
HS_FBLIM1; -
; .
ExpressionAtlas
Q8WUP2; baseline and differential
; .
Genevisible
Q8WUP2; HS
; .
GO
GO:0005938; C:cell cortex
; IEA:UniProtKB-SubCell; .
GO
GO:0030054; C:cell junction
; IDA:HPA; .
GO
GO:0005829; C:cytosol
; TAS:Reactome; .
GO
GO:0001650; C:fibrillar center
; IDA:HPA; .
GO
GO:0005925; C:focal adhesion
; IDA:UniProtKB; .
GO
GO:0001725; C:stress fiber
; IDA:UniProtKB; .
GO
GO:0031005; F:filamin binding
; IDA:UniProtKB; .
GO
GO:0008270; F:zinc ion binding
; IEA:InterPro; .
GO
GO:0034329; P:cell junction assembly
; TAS:Reactome; .
GO
GO:0008360; P:regulation of cell shape
; IEA:UniProtKB-KW; .
GO
GO:0033623; P:regulation of integrin activation
; IMP:UniProtKB; .
GO
GO:0016337; P:single organismal cell-cell adhesion
; IMP:UniProtKB; .
Gene3D
2.10.110.10; -
; 3; .
InterPro
IPR001781; Znf_LIM
; .
Pfam
PF00412; LIM
; 3; .
SMART
SM00132; LIM
; 3; .
PROSITE
PS00478; LIM_DOMAIN_1
; 3; .
PROSITE
PS50023; LIM_DOMAIN_2
; 3; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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